Docetaxel相关论文
Continuous docetaxel (DTX) treatment of non-small cell lung cancer induces development of drug resistance,but the mechan......
目的 观察多西他赛静脉化疗联合奈达铂动脉介入栓塞治疗中晚期宫颈癌的效果，探析药物作用机制?方法 回顾性分析选择2016年4月至2017......
Intermittent tri-weekly docetaxel plus bicalutamide in patients with castration-resistant prostate c
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PSA time to nadir as a prognostic factor of first-line docetaxel treatment in castration-resistant p
Docetaxel-based chemotherapy remains the first-line treatment for patients with metastatic castration-resistant prostate......
The development and progression of metastatic castration-resistant prostate cancer is the major challenge in the treatme......
Chemotherapy in prostate cancer (PCa) has undergone dramatic landscape changes.While earlier studies utilized varying ch......
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prostate cancer has been recognized as being responsive to androgen deprivation since the 1940s when Charles Huggins ifr......
Co-delivery of siRNA and docetaxel into tumor by polypeptide micelles based on PEG-PLL-PLLeu tribloc
Combination of two or more therapeutic strategies with different mechanisms can cooperatively impede cancer development.......
pH-sensitive docetaxel-loaded TPGS-poly(β-amino ester) copolymer nanoparticles for overcoming multid
Multidrug resistance (MDR) is one of the major obstacles to successful chemotherapy.Overexpression of drug efflux transp......
在可回收和重复使用的手性催化剂(QN)2 PHAL-PEG-OMe-OOsO3K存在下,以肉桂酸甲酯为原料通过Sharpless不对称双羟化反应的关键步骤......
pH-triggered charge-reversal and redox-responsive nanoparticles for docetaxel delivery in hepatocell
The insufficient cellular uptake of nanocarriers and their slow drug release have become major obstacles for achieving s......
Local administration of microtubule-targeting agent promote motor functional recovery after spinal c
Spinal cord injury (SCI) is a devastating traumatic event which can lead to a range of health problems beyond sensory an......
Dendrimers are highly branched,symmetrical macromolecules of nano-sized dimensions,consisting of a central core,repeatin......
Background Docetaxel (DTX), a potent anticancer drug, limited in clinical usage by strong toxicity and side effect, was ......
A Randomized Controlled Phase II Trial of Vinorelbine plus Capecitabine Versus Docetaxel plus Capeci
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目的 探讨前列腺癌化疗药物docetaxel 产生抵抗的机制。方法 本实验采用克隆形成实验、细胞活力测定、细胞免疫荧光以及western bl......
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Purpose:Thisstudyaimedtodevelopanewinterventionaloncologytechnique,namely“radiofrequencyheat(RFH)-enhanced localchemoth......
Anti-PD-1/PD-L1antibodyforpretreatedadvancednon-small-celllungcancer:ameta-analysisofran
目的 ThisstudyevaluatedtheefficacyandsafetyofantiPD-1/PD-L1antibodyforpretreatedpatientswithadvancednon-smallcelllungcan......
Codelivery of Docetaxel and Ceramide Enhanced Synergistic Cancer Therapy by Lipid-based Nanosuspensi
Combination therapy as novel therapeutic strategies has attracted great attention in the field of anti-cancer therapy.Th......
Cytosolic co-delivery of miRNA-34a and docetaxel by core-shell nanocarriers for synergistic breast c
Breast cancer is the leading cause of cancer death in women worldwide,and metastasis-related recurrence accounts for ove......
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large number of lead compounds have low solubility in water,which greatly hinders their clinical application.Recently,na......
Objective:To explore the clinical curative treatment effect of liver cancer with polyene paclitaxel combined iodized oil......
Submicron emulsions (SEs) is an advanced formulation that possesses good biocompatibility, high loading of hydrophobic d......
Synergistic and attenuated effect of active protein P23 in combination treatment with docetaxel plus
Aim Platinum based combination regimens are firstline treatment option in treatment of NSCLC but the clinical utility ha......
Efficacy of radical prostatectomy combined with neoadjuvant chemotherapy in the treatment of locally
Objective: To investigate the clinical efficacy of retropubic radical prostatectomy subsequent to neoadjuvant chemothera......
CD47 peptide-modified solid lipid nanoparticles loading docetaxel with a prolonged systemic circulat
Purpose: To prepare docetaxel(DTX)-loaded,antiphagocytosis peptide(Pep CD47)-modified solid lipid nanoparticles(SLNs)wit......
Cisplatin and Fluorouracil Alone or with Docetaxel in Nasopharyngeal carcinoma:Interim Analysis of a
Background:A randomized phase 3 trial of the treatment of nasopharyngeal carcinoma compared induction chemotherapy with ......
Folic acid mediated solid lipid nanocarriers loaded with docetaxel and oxidised single-walled carbon
Single-walled Carbon nanotubes (SWNT) has large near-infrared absorption coefficient, large surface area and has shown g......
RGD-mediated,chitosan modified single-walled carbon nanotubes for docetaxel targeting delivery to in
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A new minimally invasive interventional oncology technique radiofrequency heat(RFH)was associated to improve the chemoth......
Lipid Microbubbles Loaded Docetaxel(LDLM)Combined With Ultrasound-Targeted Microbubble Destruction I
aims Ultrasound microbubbles are now being used as carriers of drugs or genes in targeted treatment of carcinoma.The pur......
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Docetaxel loaded Pluronic P105/F127 mixed micelles against Drug-Resistant Lung Adenocarcinoma Cell L
The aim of this study was to investigate the antitumor effect of docetaxel (DTX) loaded Pluronic P105/F127 mixed micelle......
Objective:to promote the application of methoxy poly (ethylene glycol)-cholesterol (mPEG-CHOL) in hydrophobic drugs load......
Docetaxel-incorporated calcium phosphate nanoparticles for lung cancer treatment:synthesis, characte
Lung cancer is a disease characterized by uncontrolled cell growth in tissues of the lung.As an antineoplastic agent,doc......
Surface-enhanced Raman spectroscopy of serum predicts sensitivity to docetaxel-based chemotherapy in
Docetaxel-based chemotherapy, as the first-line treatment for metastatic castration-resistant prostate cancer (mCRPC), h......
目的探讨新辅助内分泌治疗联合化疗(NCHT)对极高危局部进展期前列腺癌的临床疗效。方法回顾性分析上海交通大学医学院附属仁济医院......
Unresectable esophageal cancer treated with multiple chemotherapies in combination with chemoradioth
BACKGROUND Definitive chemoradiotherapy(dCRT)using cisplatin plus 5fluorouracil(CF)with radiation is considered the stan......
Small changes in the length of diselenide bond-containing linkages exert great influences on the ant
Homodimeric prodrug-based self-assembled nanoparticles,with carrier-free structure and ultrahigh drug loading,is drawing......
ST6Gal-Ⅰ Modulates Docetaxel Sensitivity in Human Hepatocarcinoma Cells via the p38 MAPKcaspase Path
The β-galactoside α2-6-sialyltransferase 1 (ST6Gal-Ⅰ) is the principal sialyltransferase responsible for the addi......
目的:探索乳腺癌患者接受体表面积(BSA)指导用药剂量的多西他赛(DTX)化疗后患者体内药代动力学多态性,以揭示患者体内药物暴露的差......
docetaxel（商品名Taxotere）是一种新的半合成的紫杉醇类衍生物，其促进微管蛋白装配和抑制微管解聚的能力为紫杉醇的2倍。在临床前试验......
一项由加拿大牵头的国际研究发现,采用新一代药物 docetaxel 治疗可使晚期前列腺癌患者的生存期延长数月,并可改善患者的生存质量......
Objective:To study the inhibitory effect of docetaxel(DOC),oxaliplatin(OXA)and their combination on proliferation of cer......
